HISTORY OF ANTISENSE OLIGONUCLEOTIDES

By D. KIVAO

Contents Chapter 1 Origins of Antisense Research 1 Chapter 2 Experimental Milestones in Antisense Development 24 Chapter 3 Technological Progress in Therapeutic Design 46 Chapter 4 Clinical Translation and Regulatory Evolution 73 Chapter 5 Scientific Impact Across Biomedical Research 97 Chapter 6 Emerging Directions and Historical Legacy 125