PHARMACEUTICAL FORMULATION

By THOMAS LEE

CONTENTS 1 INTRODUCTION AND PERSPECTIVE 2 AIDING CANDIDATE DRUG SELECTION: INTRODUCTION AND OBJECTIVES 3 PREFORMULATION INVESTIGATIONS USING SMALL AMOUNTS OF COMPOUND AS AN AID TO CANDIDATE DRUG SELECTION AND EARLY DEVELOPMENT 4 BIOPHARMACEUTICAL SUPPORT IN CANDIDATE DRUG SELECTION 5 EARLY DRUG DEVELOPMENT: PRODUCT DESIGN 6 PREFORMULATION AS AN AID TO PRODUCT DESIGN IN EARLY DRUG DEVELOPMENT 7 BIOPHARMACEUTICAL SUPPORT IN FORMULATION DEVELOPMENT 8 PRODUCT OPTIMIZATION 9 PARENTERAL DOSAGE FORMS 10 INHALATION DOSAGE FORMS 11 ORAL SOLID DOSAGE FORMS 12 OPHTHALMIC DOSAGE FORMS 13 AQUEOUS NASAL DOSAGE FORMS 14 TOPICAL AND TRANSDERMAL DELIVERY