THE PARADOX OF PRION DISEASE
1 KURU: INTRODUCTION TO PRION DISEASES 2 ANTHROPOLOGICAL METHODS USED IN KURU RESEARCH 3 NONHUMAN PRIMATES IN RESEARCH ON TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES 4 CLINICAL FEATURES AND DIAGNOSIS OF HUMAN PRION DISEASES 5 NEUROPATHOLOGY, IMMUNOHISTOCHEMISTRY, AND BIOCHEMISTRY IN HUMAN PRION DISEASES 6 SUBCELLULAR AND MOLECULAR CHANGES ASSOCIATED WITH ABNORMAL PRP ACCUMULATION IN BRAIN AND VISCERA OF CLASSICAL AND ATYPICAL PRION DISEASES 7 ELECTRON MICROSCOPY OF PRION DISEASES 8 CELL DEATH AND AUTOPHAGY IN PRION DISEASES 9 METHODS FOR ISOLATION OF SPIROPLASMA SP FROM PRION-POSITIVE EYE TISSUES OF SHEEP AFFECTED WITH TERMINAL SCRAPIE 10 DETECTION AND DIAGNOSIS OF PRION DISEASES USING RT-QUIC: AN UPDATE 11 ANALYSIS OF CHARGE ISOFORMS OF THE SCRAPIE PRION PROTEIN USING TWO- DIMENSIONAL ELECTROPHORESIS 12 EXOSOMES IN PRION DISEASES CONTENTS 13 SYNTHETIC MAMMALIAN PRIONS 14 BIOMARKERS IN CEREBROSPINAL FLUID 15 THE USE OF TRANSGENIC AND KNOCKOUT MICE IN PRION RESEARCH 16 TRANSGENIC MOUSE MODELS OF PRION DISEASES