OVARIAN CANCER: METHODS AND PROTOCOLS
Part I Chemoprevention, Staging, and Novel Therapeutic Targets 1 Chemoprevention of Ovarian Cancer 3 2 Staging and Surgical Treatment 35 3 Novel Therapeutic Targets 63 4 Biomarker Targets and Novel Therapeutics 85 Part II Tumorigenesis and Biomarkers 5 Tumor Suppressor Genes 109 6 Epigenetics and Ovarian Cancer 131 7 Aberrant Epithelial Differentiation in Ovarian Cancer 147 8 The Human Kallikrein Gene Family: New Biomarkers for Ovarian Cancer 165 9 Soluble Epidermal Growth Factor Receptor: A Biomarker of Epithelial Ovarian Cancer 189 10 Activated Epidermal Growth Factor Receptor in Ovarian Cancer 203 Part III Tumor Progression, Metastasis, Research Models 11 Ras-Superfamily GTP-ases in Ovarian Cancer 229 12 Lipid Generation and Signaling in Ovarian Cancer 241 13 Lysophosphatidic Acid and Invasion 269 14 Cell Adhesion in Ovarian Cancer 297 15 Microenvironmental Regulation of Ovarian Cancer Metastasis 319 16 Organotypic Models of Metastasis: A Three-dimensional Culture Mimicking the Human Peritoneum and Omentum for the Study of the Early Steps of Ovarian Cancer Metastasis 335 17 Animal Models of Ovarian Cancer 353