MOLECULAR MECHANISMS OF CANCER
CONTENTS INTRODUCTION SECTION I GENERAL MECHANISMS OF TRANSFORMATION 1 THEORIES OF CARCINOGENESIS 2 PHYSIOLOGIC CORRELATES OF MALIGNANCY SECTION II ALTERATIONS INTRINSIC TO THE TUMOR CELLS 3 CELL DIVISION AND SURVIVAL 4 CELLULAR SENESCENCE 5 INVASIVENESS SECTION III MECHANISMS OF REGULATION OF CANCER-RELATED GENES 6 DNA REPAIR 7 EPIGENETIC REGULATION OF CANCER-ASSOCIATED GENE PRODUCTS 8 INTERACTION OF THE GROUPS OF CANCER-RELATED GENE PRODUCTS SECTION IV INTERACTIONS BETWEEN HOST AND TUMOR 9 STRUCTURAL GROWTH CONTROL 10 THE ORGAN PREFERENCE OF METASTASIS FORMATION 11 ANGIOGENESIS 12 INTERACTIONS WITH THE IMMUNE SYSTEM 13 ENDOCRINE DYSREGULATION 14 DORMANCY AND MINIMAL RESIDUAL DISEASE SECTION V MOLECULAR MECHANISMS OF INDIVIDUAL MALIGNANCIES 15 EPITHELIAL TUMORS 16 HEMATOLOGIC MALIGNANCIES 17 MESENCHYMAL TUMORS 18 NEUROLOGIC TUMORS 19 TUMORS OF SEROUS CAVITIES 20 EMBRYONIC TUMORS