CURRENT PROBLEMS IN IMMUNOLOGY

By U. KUKAN

CONTENTS 1 INTRODUCTION: TUMOR AND THE HOST IMMUNE SYSTEM 2 T CELL-BASED IMMUNOTHERAPY 3 NK CELL-BASED IMMUNOTHERAPY 4 THE BASICS OF CANCER IMMUNITY DC-BASED IMMUNOTHERAPY: GLIOMAS AS A PARADIGM DISEASE? 5 CYTOKINES IN CANCER IMMUNOTHERAPY: THE YIN AND YANG ASPECTS OF IL-12 FAMILY OF CYTOKINES 6 GENETICALLY ENGINEERED T CELL IMMUNOTHERAPY FOR GLIOMAS AND OTHER SOLID TUMORS 7 THERAPEUTIC ANTIBODY ENGINEERING 8 INTERFERON-ALFA AS A VACCINE ADJUVANT 9 TARGETING T CELL COSTIMULATION 10 REGENERATION OF TUMOR ANTIGEN-SPECIFIC T CELLS USING IPSC TECHNOLOGY 11 NEUTRALIZING REGULATORY T CELLS 12 CANCER VACCINES: CURRENT STATUS AND FUTURE PERSPECTIVES 13 SUMMARY AND SHORT-TERM OUTLOOK PART