NUTRIGENOMICS AND PROTEOMICS IN HEALTH AND DISEASE

By WILLIAM LOPEZ

CONTENTS SECTION I INTRODUCTION 1 NUTRIGENOMICS AND PROTEOMICS IN HEALTH AND DISEASE: AN OVERVIEW 2 OMICS IN NUTRITION AND HEALTH RESEARCH SECTION II GENOMICS AND PROTEOMICS IN HEALTH AND DISEASES 3 TOWARD PERSONALIZED NUTRITION AND MEDICINE: PROMISES AND CHALLENGES 4 OBESITY AND NUCLEAR RECEPTORS: EFFECTIVE GENOMIC STRATEGIES IN FUNCTIONAL FOODS 5 IN?AMMATORY GENES INVOLVED IN OBESITY-INDUCED IN?AMMATORY RESPONSES AND PATHOLOGIES 6 GENOMICS AND PROTEOMICS IN ALLERGY SECTION III FOOD FACTORS–GENE INTERACTIONS 7 BENE?CIAL EFFECTS OF CONJUGATED LINOLEIC ACID 8 REGULATION OF GENE TRANSCRIPTION BY FATTY ACIDS 9 NONNUTRIENT FUNCTIONALITY OF AMINO ACIDS 10 FUNCTIONAL BIOACTIVE PROTEINS AND PEPTIDES IN NUTRIGENOMICS 11 ANTIOBESITY EFFECT OF ALLENIC CAROTENOID, FUCOXANTHIN 12 CONTROL OF SYSTEMIC IN?AMMATION AND CHRONIC DISEASES—THE USE OF TURMERIC AND CURCUMINOIDS 13 ALTERATION IN GENE EXPRESSION AND PROTEOMIC PRO?LES BY SOY ISO?AVONE 14 GREEN TEA POLYPHENOL-MODULATED GENOME FUNCTIONS FOR PROTECTIVE HEALTH BENE?TS 15 OAT AVENANTHRAMIDES: A NOVEL ANTIOXIDANT 16 CANCER-PREVENTIVE EFFECTS AND MOLECULAR ACTIONS OF ANTHOCYANINS 18 NEW THERAPEUTIC EFFECTS OF ANTHOCYANINS: ANTIOBESITY EFFECT, ANTIDIABETES EFFECT, AND VISION IMPROVEMENT 19 LICORICE FLAVONOIDS 20 ISOPRENOLS 21 ANTI-IN?AMMATORY AND ANTICARCINOGENESIS POTENTIALS OF CITRUS COUMARINS AND POLYMETHYLATED FLAVONOIDS 22 PROBIOTICS: FOOD FOR THOUGHT SECTION IV ADVANCED ANALYTICAL TECHNIQUES FOR NUTRIGENOMICS AND PROTEOMICS 23 MICROARRAYS: A POWERFUL TOOL FOR STUDYING THE FUNCTIONS OF FOOD AND ITS NUTRIENTS 24 CHALLENGES AND CURRENT SOLUTIONS IN PROTEOMIC SAMPLE PREPARATIONS 25 COMPUTATIONAL METHODS IN CANCER GENE NETWORKING 26 PEPTIDOMICS