THE ENDEMIC DISEASES OF THE SOUTHERN STATES

By JOHN RAMIREZ

CONTENTS ON FRAMING THE RESEARCH QUESTION AND CHOOSING THE APPROPRIATE RESEARCH DESIGN BIAS IN CLINICAL RESEARCH DE?NITIONS OF BIAS IN CLINICAL RESEARCH RESEARCH ETHICS FOR CLINICAL RESEARCHERS ETHICAL, LEGAL, AND SOCIAL ISSUES (ELSI) IN CLINICAL GENETICS RESEARCH LONGITUDINAL STUDIES 1: DETERMINANTS OF RISK LONGITUDINAL STUDIES 2: MODELING DATA USING MULTIVARIATE ANALYSIS LONGITUDINAL STUDIES 3: DATA MODELING USING STANDARD REGRESSION MODELS AND EXTENSIONS LONGITUDINAL STUDIES 4: MATCHING STRATEGIES TO EVALUATE RISK LONGITUDINAL STUDIES 5: DEVELOPMENT OF RISK PREDICTION MODELS FOR PATIENTS WITH CHRONIC DISEASE RANDOMIZED CONTROLLED TRIALS 1: DESIGN RANDOMIZED CONTROLLED TRIALS 2: ANALYSIS RANDOMIZED CONTROLLED TRIALS 3: MEASUREMENT AND ANALYSIS OF PATIENT-REPORTED OUTCOMES RANDOMIZED CONTROLLED TRIALS 4: PLANNING, ANALYSIS, AND INTERPRETATION OF QUALITY-OF-LIFE STUDIES RANDOMIZED CONTROLLED TRIALS 5: BIOMARKERS AND SURROGATES/OUTCOMES RANDOMIZED CONTROLLED TRIALS 6: DETERMINING THE SAMPLE SIZE AND POWER FOR CLINICAL TRIALS AND COHORT STUDIES RANDOMIZED CONTROLLED TRIALS 7: ON CONTAMINATION AND ESTIMATING THE ACTUAL TREATMENT EFFECT EVALUATION OF DIAGNOSTIC TESTS GENETIC EPIDEMIOLOGY OF COMPLEX PHENOTYPES QUALITATIVE RESEARCH IN CLINICAL EPIDEMIOLOGY EVIDENCE-BASED DECISION-MAKING 1: CRITICAL APPRAISAL EVIDENCE-BASED DECISION-MAKING 2: SYSTEMATIC REVIEWS AND META-ANALYSIS EVIDENCE-BASED DECISION MAKING 3: HEALTH TECHNOLOGY ASSESSMENT EVIDENCE-BASED DECISION MAKING 4: CLINICAL PRACTICE GUIDELINES EVIDENCE-BASED DECISION MAKING 5: KNOWLEDGE TRANSLATION AND THE KNOWLEDGE TO ACTION CYCLE EVIDENCE-BASED DECISION MAKING 6: ADMINISTRATIVE DATABASES AS SECONDARY DATA SOURCE FOR EPIDEMIOLOGIC AND HEALTH SERVICE RESEARCH EVIDENCE-BASED DECISION MAKING 7: HEALTH ECONOMICS IN CLINICAL RESEARCH EVIDENCE-BASED DECISION-MAKING 8: A PRIMER ON HEALTH POLICY FOR RESEARCHERS CHANGING HEALTH-RELATED BEHAVIORS 1: PATIENT-ORIENTED RESEARCH AND PATIENT ENGAGEMENT IN HEALTH RESEARCH CHANGING HEALTH-RELATED BEHAVIORS 2: ON IMPROVING THE VALUE OF HEALTH SPENDING CHANGING HEALTH-RELATED BEHAVIORS 3: LESSONS FROM IMPLEMENTATION SCIENCE CHANGING HEALTH-RELATED BEHAVIORS 4: REALIZING IMPACT OF HEALTH RESEARCH THROUGH KNOWLEDGE TRANSLATION CHANGING HEALTH-RELATED BEHAVIOURS 5: ON INTERVENTIONS TO CHANGE PHYSICIAN BEHAVIOURS CHANGING HEALTH-RELATED BEHAVIORS 6: ANALYSIS, INTERPRETATION, AND APPLICATION OF BIG DATA