CHEMICALS CONTROLLING INSECT BEHAVIOR

By S. FIORD

PART 1 MOLECULAR SIGNALING MECHANISMS: FROM PATHWAYS TO NETWORKS 1 WNT SIGNAL PRODUCTION, SECRETION, AND DIFFUSION 2 WNT SIGNALING AT THE MEMBRANE 3 WNT SIGNAL TRANSDUCTION IN THE CYTOPLASM: AN INTRODUCTION TO THE DESTRUCTION COMPLEX 4 AN OVERVIEW OF GENE REGULATION BY WNT/?-CATENIN SIGNALING 5 FINDING A NEEDLE IN A GENOMIC HAYSTACK: GENOME-WIDE APPROACHES TO IDENTIFY WNT/TCF TRANSCRIPTIONAL TARGETS 6 INTRODUCTION TO ?-CATENIN-INDEPENDENT WNT SIGNALING PATHWAYS 7 MOLECULAR MECHANISMS OF WNT PATHWAY SPECIFICITY 8 MODULATION OF WNT SIGNALING BY ENDOCYTOSIS OF RECEPTOR COMPLEXES 9 NEW INSIGHTS FROM PROTEOMIC ANALYSIS OF WNT SIGNALING 10 NEW INSIGHTS ABOUT WNT/?-CATENIN PATHWAY MECHANISMS FROM GLOBAL SIRNA SCREENS 11 MATHEMATICAL MODELS OF WNT SIGNALING PATHWAYS 12 THE WNT’S TALE: ON THE EVOLUTION OF A SIGNALING PATHWAY CONTENTS PART 2 SELECTED KEY MOLECULES IN WNT SIGNALING 13 SECRETED WNT INHIBITORS OR MODULATORS 14 FRIZZLEDS AS G PROTEIN-COUPLED RECEPTORS 15 DISHEVELLED AT THE CROSSROADS OF PATHWAYS ?EJ BERNATÍK 16 ?-CATENIN: A KEY PLAYER IN BOTH CELL ADHESION AND WNT SIGNALING 17 EVOLUTIONARY DIVERSIFICATION OF VERTEBRATE TCF/LEF STRUCTURE, FUNCTION, AND REGULATION 18 INSIGHTS FROM STRUCTURAL ANALYSIS OF PROTEIN–PROTEIN INTERACTIONS BY WNT PATHWAY COMPONENTS AND FUNCTIONAL MULTIPROTEIN COMPLEX FORMATION PART 3 WNT SIGNALING IN EMBRYONIC DEVELOPMENT AND ADULT TISSUE HOMEOSTASIS 19 WNT SIGNALING IN EARLY VERTEBRATE DEVELOPMENT: FROM FERTILIZATION TO GASTRULATION 20 WNT/?-CATENIN SIGNALING IN EMBRYONIC STEM CELLS: INSIGHTS INTO EARLY MAMMALIAN DEVELOPMENT 21 WNT SIGNALING IN NEURAL DEVELOPMENT 22 WNT SIGNALING IN HEART ORGANOGENESIS 23 WNT SIGNALING IN KIDNEY ORGANOGENESIS 24 WNT SIGNALING REGULATION OF TISSUE ARCHITECTURE (EMT AND MET) AND MORPHOGENESIS: CONSEQUENCES FOR COLORECTAL AND LIVER CANCER 25 WNT SIGNALING IN ADULT STEM CELLS: TISSUE HOMEOSTASIS AND REGENERATION 26 RESTORING TISSUE HOMEOSTASIS: WNT SIGNALING IN TISSUE REGENERATION AFTER ACUTE INJURY PART 4 WNT SIGNALING IN CHRONIC DISEASE 27 WNT SIGNALING AND COLORECTAL CANCER 28 WNT SIGNALING IN MELANOMA 29 WNT SIGNALING IN MOOD AND PSYCHOTIC DISORDERS 30 NEUROPSYCHIATRIC DISEASE-ASSOCIATED GENETIC VARIATION IN THE WNT PATHWAY 31 WNT SIGNALING IN DEMENTIA 32 THERAPEUTIC TARGETING OF THE WNT SIGNALING NETWORK