PEPTIDE THIOESTER SUBSTRATES FOR SERINE PEPTIDASES AND METALLOENDOPEPTIDASES

By SUSAN MARTIN

Contents Chapter 1 Structural Chemistry and Enzymatic Principles 1 Chapter 2 Design and Synthesis of Thioester Substrates 28 Chapter 3 Kinetic Analysis and Mechanistic Investigations 51 Chapter 4 Experimental Methodologies and Analytical Technologies 78 Chapter 5 Biological Applications and Functional Studies 109 Chapter 6 Translational Research and Emerging Innovations 135