CELL ENGINEERING

By N. FITIU

CONTENTS 1 CASPASE REGULATION AT THE MOLECULAR LEVEL 2 THE BCL-2 FAMILY 3 THE IGF-1 RECEPTOR IN CELLS SURVIVAL: SIGNALLING AND REGULATION 4 APOPTOSIS IN HEPATOCYTES 5 PROGRAMMED CELL DEATH IN PLANTS DURING DEVELOPMENT AND STRESS RESPONSES 6 A SYSTEMS VIEW OF CELL DEATH 7 THE ROLE OF CASPASES IN APOPTOSIS AND THEIR INHIBITION IN MAMMALIAN CELL CULTURE 8 IMPROVEMENT OF INDUSTRIAL CELL CULTURE PROCESSES BY CASPASE- 9 DOMINANT NEGATIVE AND OTHER APOPTOTIC INHIBITORS 10 APOPTOSIS CONTOL BASED ON DOWN-REGULATING THE INHIBITOR-OF-APOPTOSIS (IAP) PROTEINS: XIAP ANTISENSE AND OTHER APPROACHES 11 MONITORING OF APOPTOSIS 12 MOLECULAR IMAGING OF PROGRAMMED CELL DEATH; FROM BASIC MECHANISMS TO CLINICAL APPLICATIONS