INTRODUCTION TO PROTEOMICS

By N. FIIRY

1 PROTEOMICS AND THE NEW BIOLOGY 2 THE PROTEOME 3 OVERVIEW OF ANALYTICAL PROTEOMICS 4 ANALYTICAL PROTEIN AND PEPTIDE SEPARATIONS 5 PROTEIN DIGESTION TECHNIQUES 6 MASS SPECTROMETERS FOR PROTEIN AND PEPTIDE ANALYSIS 7 PROTEIN IDENTIFICATION BY PEPTIDE MASS FINGERPRINTING 8 PEPTIDE SEQUENCE ANALYSIS BY TANDEM MASS SPECTROMETRY 10 SALSA: AN ALGORITHM FOR MINING SPECIFIC FEATURES OF TANDEM MS DATA 11 MINING PROTEOMES 12 PROTEIN EXPRESSION PROFILING 13 IDENTIFYING PROTEIN–PROTEIN INTERACTIONS AND PROTEIN COMPLEXES 14 MAPPING PROTEIN MODIFICATIONS 15 NEW DIRECTIONS IN PROTEOMICS