HANDBOOK OF PESTICIDES AND AGRICULTURAL CHEMICALS

By K. FIZIR

CONTENTS INTRODUCTION AND OVERVIEW SECTION ONE: EXPOSURE ASSESSMENT METHODOLOGIES 1 ASSESSMENT OF EXPOSURE FOR PESTICIDE HANDLERS IN AGRICULTURAL, RESIDENTIAL AND INSTITUTIONAL ENVIRONMENTS 2 DEVELOPMENT OF RISK-BASED RESTRICTED ENTRY INTERVALS 3 RESIDENTIAL POST-APPLICATION PESTICIDE EXPOSURE MONITORING 4 RESIDENTIAL (NON-DIETARY) POST-APPLICATION EXPOSURE ASSESSMENT SECTION TWO: DATABASES AND MODELS 5 GENERIC OPERATOR EXPOSURE DATABASES 6 PREDICTIVE RESIDENTIAL MODELS SECTION THREE: EPIDEMIOLOGY 7 EXPOSURE ASSESSMENT FOR PESTICIDES IN EPIDEMIOLOGICAL STUDIES SECTION FOUR: ADVANCES IN DATA INTERPRETATION 8 PROBABILISTIC APPROACHES TO AGGREGATE AND CUMULATIVE RISK ASSESSMENT 9 DERMAL ABSORPTION OF PESTICIDES 10 OCCUPATIONAL AND RESIDENTIAL EXPOSURE ASSESSMENT FOR PESTICIDES – TOWARDS A HARMONIZED REGULATORY APPROACH INTRODUCTION AND OVERVIEW ASSESSMENT OF RISKS TO HUMANS EXPOSED TO PESTICIDES THE FOUR STEPS IN RISK ASSESSMENT HAZARD IDENTI?CATION DOSE–RESPONSE ASSESSMENT MARGIN OF SAFETY APPROACH QUANTITATIVE RISK ASSESSMENT EXPOSURE ASSESSMENT RISK CHARACTERIZATION RISK MANAGEMENT ADVANCES IN DATA INTERPRETATION PROBABILISTIC APPROACHES RECOGNITION OF THE TIER APPROACH AGGREGATE EXPOSURE CUMULATIVE EXPOSURE IMPACT OF NEW SCIENTI?C ADVANCES POST-REGISTRATION MONITORING HARMONIZATION OF REGULATORY APPROACHES SUMMARY